{"id":4966,"date":"2023-03-28T13:16:58","date_gmt":"2023-03-28T11:16:58","guid":{"rendered":"https:\/\/www.jphres.org\/?p=4966"},"modified":"2023-04-02T14:07:17","modified_gmt":"2023-04-02T12:07:17","slug":"occurrence-and-control-of-genotoxins-in-drinking-water-a-monitoring-proposal","status":"publish","type":"page","link":"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/769\/","title":{"rendered":"Occurrence and control of genotoxins in drinking water: a monitoring proposal"},"content":{"rendered":"<div class=\"item doi\"><span class=\"value\"><a href=\"https:\/\/doi.org\/10.4081\/jphr.2016.769\">https:\/\/doi.org\/10.4081\/jphr.2016.769<\/a><\/span><\/div>\n<ul class=\"item authors\">\n<li><span class=\"name\"><strong>Elisabetta Ceretti<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Massimo Moretti<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Italy.<br \/>\n<\/span><span class=\"orcid\"><a href=\"http:\/\/orcid.org\/0000-0002-5038-8619\" target=\"_blank\" rel=\"noopener\">http:\/\/orcid.org\/0000-0002-5038-8619<\/a><\/span><\/li>\n<li><span class=\"name\"><strong>Ilaria Zerbini<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Milena Villarini<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Claudia Zani<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Silvano Monarca<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Donatella Feretti<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy.<\/span><\/li>\n<\/ul>\n<div class=\"item abstract\">\n<h3 class=\"label\">ABSTRACT<\/h3>\n<p>Many studies have shown the presence of numerous organic genotoxins and carcinogens in drinking water. These toxic substances derive not only from pollution, but also from the disinfection treatments, particularly when water is obtained from surface sources and then chlorinated. Most of the chlorinated compounds in drinking water are nonvolatile and are difficult to characterize. Thus, it has been proposed to study such complex mixtures using short-term genotoxicity tests predictive of carcinogenic activity. Mutagenicity of water before and after disinfection has mainly been studied by the Salmonella\/microsome (Ames test); in vitro genotoxicity tests have also been performed in yeasts and mammalian cells; in situ monitoring of genotoxins has also been performed using complete organisms such as aquatic animals or plants (in vivo). The combination of bioassay data together with results of chemical analyses would give us a more firm basis for the assessment of human health risks related to the consumption of drinking water. Tests with different genetic end-points complement each other with regard to sensitivity toward environmental genotoxins and are useful in detecting low genotoxicity levels which are expected in drinking water samples.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>https:\/\/doi.org\/10.4081\/jphr.2016.769 Elisabetta Ceretti Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy. Massimo Moretti Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Italy. http:\/\/orcid.org\/0000-0002-5038-8619 Ilaria Zerbini Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy. Milena Villarini Department of Medical &#8230; <a title=\"Occurrence and control of genotoxins in drinking water: a monitoring proposal\" class=\"read-more\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/769\/\" aria-label=\"More on Occurrence and control of genotoxins in drinking water: a monitoring proposal\">Read more<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-4966","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Occurrence and control of genotoxins in drinking water: a monitoring proposal - Journal of Public Health Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/769\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Occurrence and control of genotoxins in drinking water: a monitoring proposal - Journal of Public Health Research\" \/>\n<meta property=\"og:description\" content=\"https:\/\/doi.org\/10.4081\/jphr.2016.769 Elisabetta Ceretti Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy. Massimo Moretti Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Italy. http:\/\/orcid.org\/0000-0002-5038-8619 Ilaria Zerbini Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy. Milena Villarini Department of Medical ... 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Massimo Moretti Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Italy. http:\/\/orcid.org\/0000-0002-5038-8619 Ilaria Zerbini Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy. Milena Villarini Department of Medical ... 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