{"id":4770,"date":"2023-03-28T16:42:49","date_gmt":"2023-03-28T14:42:49","guid":{"rendered":"https:\/\/www.jphres.org\/?p=4770"},"modified":"2023-04-02T14:05:59","modified_gmt":"2023-04-02T12:05:59","slug":"hospitalization-and-mortality-trends-among-patients-with-confirmed-covid-19-in-the-united-states-april-through-august-2020","status":"publish","type":"page","link":"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/2244\/","title":{"rendered":"Hospitalization and mortality trends among patients with confirmed COVID-19 in the United States, April through August 2020"},"content":{"rendered":"<div class=\"item doi\"><span class=\"value\"><a href=\"https:\/\/doi.org\/10.4081\/jphr.2021.2244\">https:\/\/doi.org\/10.4081\/jphr.2021.2244<\/a><\/span><\/div>\n<ul class=\"item authors\">\n<li><span class=\"name\"><strong>Jennifer L. Nguyen<\/strong><br \/>\n<span class=\"affiliation\">Pfizer Inc, New York, NY, United States.<\/span><span class=\"orcid\"><br \/>\n<a href=\"https:\/\/orcid.org\/0000-0002-4064-0227\" target=\"_blank\" rel=\"noopener\">https:\/\/orcid.org\/0000-0002-4064-0227<\/a><\/span><\/span><\/li>\n<li><span class=\"name\"><strong>Michael Benigno<\/strong><br \/>\n<\/span><span class=\"affiliation\">Pfizer Inc, New York, NY, United States.<\/span><\/li>\n<li><span class=\"name\"><strong>Deepa Malhotra<\/strong><br \/>\n<\/span><span class=\"affiliation\">Pfizer Inc, New York, NY, United States.<\/span><\/li>\n<li><span class=\"name\"><strong>Maya Reimbaeva<\/strong><br \/>\n<\/span><span class=\"affiliation\">Pfizer Inc, New York, NY, United States.<\/span><span class=\"orcid\"><br \/>\n<a href=\"https:\/\/orcid.org\/0000-0002-1823-8995\" target=\"_blank\" rel=\"noopener\">https:\/\/orcid.org\/0000-0002-1823-8995<\/a><\/span><\/li>\n<li><span class=\"name\"><strong>Ziphora Sam<\/strong><br \/>\n<\/span><span class=\"affiliation\">Eliassen Group, Somerset, NJ, United States.<\/span><\/li>\n<li><span class=\"name\"><strong>Richard Chambers<\/strong><br \/>\n<\/span><span class=\"affiliation\">Pfizer Inc, New York, NY, United States.<\/span><\/li>\n<li><span class=\"name\"><strong>Jennifer Hammond<\/strong><br \/>\n<\/span><span class=\"affiliation\">Pfizer Inc, Collegeville, PA, United States.<\/span><\/li>\n<li><span class=\"name\"><strong>Birol Emir<\/strong><br \/>\n<\/span><span class=\"affiliation\">Pfizer Inc, New York, NY, United States.<\/span><\/li>\n<\/ul>\n<div class=\"item abstract\">\n<h3 class=\"label\">ABSTRACT<\/h3>\n<p><strong>Background:\u00a0<\/strong>The United States has experienced high COVID-19 case counts, hospitalizations, and death rates. This retrospective analysis reports changing trends in the demographics and clinical outcomes of hospitalized US COVID-19 patients between April and August 2020.<br \/>\n<strong>Design and Methods:\u00a0<\/strong>The Premier Healthcare Database Special Release was used to examine patient demographics of hospitalized COVID-19 patients from all US Census Bureau divisions. Demographics included age, sex, race, and ethnicity. Clinical outcomes included in-hospital mortality, intensive care unit (ICU) admission, and receipt of invasive mechanical ventilation.<br \/>\n<strong>Results:\u00a0<\/strong>Overall, 146,491 hospitalized COVID-19 patients were included (mean [SD] age, 61.0 [18.4] years; 51.7% male; 29.6% White non-Hispanic). Monthly total hospitalizations decreased from 44,854 in April to 18,533 in August; ICU admissions increased from 19.8% to 23.6%, and ventilator use and inpatient mortality decreased from 18.6% to 14.5% and 21.0% to 11.4%, respectively. Inpatient mortality was highest in the Middle Atlantic division (20.3%), followed by the New England (19.0%), East North Central (14.2%), and Mountain (13.7%) divisions. Black non-Hispanic patients were overrepresented among hospitalizations (19.0%); this group comprises 12.2% of the US population. Patients aged &lt;65 years made up 53% of hospitalizations and had lower inpatient mortality than those aged \u226565 years.<br \/>\n<strong>Conclusions:\u00a0<\/strong>Hospitalizations, ventilator use, and mortality decreased, while ICU admission rates increased from April to August 2020. Older individuals and Black non-Hispanics were found to be at elevated risk of severe outcomes. These trends could inform ongoing patient care and US public health policies to limit the further spread of SARS-CoV-2.<\/p>\n<h3 class=\"label\">REFERENCES<\/h3>\n<div class=\"value\">\n<p>World Health Organization. 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Hospitalization and mortality among black patients and white patients with Covid-19. N Engl J Med 2020;382:2534-43. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1056\/NEJMsa2011686\">https:\/\/doi.org\/10.1056\/NEJMsa2011686<\/a><\/p>\n<p>US Census Bureau. Accessed October 28, 2020. Available at:\u00a0<a href=\"https:\/\/data.census.gov\/cedsci\/profile?q=United%20States&amp;g=0100000US&amp;tid=ACSDP1Y2018.DP05\">https:\/\/data.census.gov\/cedsci\/profile?q=United%20States&amp;g=0100000US&amp;tid=ACSDP1Y2018.DP05<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>https:\/\/doi.org\/10.4081\/jphr.2021.2244 Jennifer L. Nguyen Pfizer Inc, New York, NY, United States. https:\/\/orcid.org\/0000-0002-4064-0227 Michael Benigno Pfizer Inc, New York, NY, United States. Deepa Malhotra Pfizer Inc, New York, NY, United States. Maya Reimbaeva Pfizer Inc, New York, NY, United States. https:\/\/orcid.org\/0000-0002-1823-8995 Ziphora Sam Eliassen Group, Somerset, NJ, United States. Richard Chambers Pfizer Inc, New York, NY, &#8230; <a title=\"Hospitalization and mortality trends among patients with confirmed COVID-19 in the United States, April through August 2020\" class=\"read-more\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/2244\/\" aria-label=\"More on Hospitalization and mortality trends among patients with confirmed COVID-19 in the United States, April through August 2020\">Read more<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-4770","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hospitalization and mortality trends among patients with confirmed COVID-19 in the United States, April through August 2020 - Journal of Public Health Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/2244\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hospitalization and mortality trends among patients with confirmed COVID-19 in the United States, April through August 2020 - Journal of Public Health Research\" \/>\n<meta property=\"og:description\" content=\"https:\/\/doi.org\/10.4081\/jphr.2021.2244 Jennifer L. Nguyen Pfizer Inc, New York, NY, United States. https:\/\/orcid.org\/0000-0002-4064-0227 Michael Benigno Pfizer Inc, New York, NY, United States. Deepa Malhotra Pfizer Inc, New York, NY, United States. Maya Reimbaeva Pfizer Inc, New York, NY, United States. https:\/\/orcid.org\/0000-0002-1823-8995 Ziphora Sam Eliassen Group, Somerset, NJ, United States. Richard Chambers Pfizer Inc, New York, NY, ... 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Nguyen Pfizer Inc, New York, NY, United States. https:\/\/orcid.org\/0000-0002-4064-0227 Michael Benigno Pfizer Inc, New York, NY, United States. Deepa Malhotra Pfizer Inc, New York, NY, United States. Maya Reimbaeva Pfizer Inc, New York, NY, United States. https:\/\/orcid.org\/0000-0002-1823-8995 Ziphora Sam Eliassen Group, Somerset, NJ, United States. Richard Chambers Pfizer Inc, New York, NY, ... 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