{"id":4456,"date":"2023-03-27T13:27:25","date_gmt":"2023-03-27T11:27:25","guid":{"rendered":"https:\/\/www.jphres.org\/?p=4456"},"modified":"2023-04-02T14:16:01","modified_gmt":"2023-04-02T12:16:01","slug":"development-of-sweet-potato-ipomoea-batatas-lamk-as-excipient-in-tablet-formulation","status":"publish","type":"page","link":"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1831\/","title":{"rendered":"Development of sweet potato (Ipomoea batatas Lamk.) as excipient in tablet formulation"},"content":{"rendered":"<div class=\"item doi\"><span class=\"value\"><a href=\"https:\/\/doi.org\/10.4081\/jphr.2020.1831\">https:\/\/doi.org\/10.4081\/jphr.2020.1831<\/a><\/span><\/div>\n<ul class=\"item authors\">\n<li><span class=\"name\"><strong>Lamia Diang Mahalia<\/strong><br \/>\n<\/span><span class=\"affiliation\">Doctoral Program of Public Health, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia.<\/span><\/li>\n<li><span class=\"name\"><strong>Stefanus Supriyanto<\/strong><br \/>\nDepartement of Health Policy and Administration, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia.<\/span><\/li>\n<li><span class=\"name\"><strong>Yandi Syukri<\/strong><br \/>\n<\/span><span class=\"affiliation\">Departement of Pharmacy, Faculty of Mathematic and Science, Universitas Islam Indonesia, Yogyakarta, Indonesia.<\/span><\/li>\n<\/ul>\n<div class=\"item abstract\">\n<h3 class=\"label\">ABSTRACT<\/h3>\n<p>Background: Sweet potato has a potential to be used as a raw material for tablets. However, it needs chemical modifications to produce derivatives with excellent pharmaceutical characteristics. The primary purpose of this research was to use sweet potato starch\u00a0<em>(Ipomoea<\/em>\u00a0<em>batatas<\/em>\u00a0Lamk.) as a tablet excipient modified through a chemical process.<\/p>\n<p>Design and Methods: This study is experimental and is divided into three stages. The first stage is the extraction process to obtain sweet potato starch. The second stage is the chemical modification of sweet potato starch using pentanol-1 and glacial acetic acid. The third step is the analysis of the pharmaceutical properties of the mutated lab model compared to the control sample and Amprotab.<\/p>\n<p>Results: The descriptive-comparative analysis showed sweet potato starch modified with panthenol-1 had a higher hardness value (=2.55\u00b10.34) compared to native starch (1.00\u00b10.08). The particle size distribution of the modified sample with acetate acid (=15.20\u00b11.79) was higher than the others.<\/p>\n<p>Conclusions: In conclusion, modified sweet potato starch has better pharmaceutical properties than native starch. Further research needs to be conducted on the magnitude of the potential of sweet potato starch as an excipient, both as filler, a binder, and a crushing agent on tablet preparations.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>https:\/\/doi.org\/10.4081\/jphr.2020.1831 Lamia Diang Mahalia Doctoral Program of Public Health, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia. Stefanus Supriyanto Departement of Health Policy and Administration, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia. Yandi Syukri Departement of Pharmacy, Faculty of Mathematic and Science, Universitas Islam Indonesia, Yogyakarta, Indonesia. ABSTRACT Background: Sweet potato has a potential &#8230; <a title=\"Development of sweet potato (Ipomoea batatas Lamk.) as excipient in tablet formulation\" class=\"read-more\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1831\/\" aria-label=\"More on Development of sweet potato (Ipomoea batatas Lamk.) as excipient in tablet formulation\">Read more<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-4456","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Development of sweet potato (Ipomoea batatas Lamk.) as excipient in tablet formulation - Journal of Public Health Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1831\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Development of sweet potato (Ipomoea batatas Lamk.) as excipient in tablet formulation - Journal of Public Health Research\" \/>\n<meta property=\"og:description\" content=\"https:\/\/doi.org\/10.4081\/jphr.2020.1831 Lamia Diang Mahalia Doctoral Program of Public Health, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia. Stefanus Supriyanto Departement of Health Policy and Administration, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia. Yandi Syukri Departement of Pharmacy, Faculty of Mathematic and Science, Universitas Islam Indonesia, Yogyakarta, Indonesia. ABSTRACT Background: Sweet potato has a potential ... 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Stefanus Supriyanto Departement of Health Policy and Administration, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia. Yandi Syukri Departement of Pharmacy, Faculty of Mathematic and Science, Universitas Islam Indonesia, Yogyakarta, Indonesia. ABSTRACT Background: Sweet potato has a potential ... 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