{"id":4248,"date":"2023-03-29T05:55:10","date_gmt":"2023-03-29T03:55:10","guid":{"rendered":"https:\/\/www.jphres.org\/?p=4248"},"modified":"2023-04-02T14:00:53","modified_gmt":"2023-04-02T12:00:53","slug":"acute-lethal-poisonings-in-children-a-10-year-retrospective-study-of-the-moscow-region-russia","status":"publish","type":"page","link":"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1932\/","title":{"rendered":"Acute lethal poisonings in children: a 10-year retrospective study of the Moscow Region, Russia"},"content":{"rendered":"<div class=\"item doi\"><span class=\"type\"><a href=\"https:\/\/doi.org\/10.4081\/jphr.2021.1932\">https:\/\/doi.org\/10.4081\/jphr.2021.1932<\/a><\/span><\/div>\n<p><span class=\"name\"><br \/>\n<strong>Semyon S. Plis<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Complex Examinations, Moscow Region Bureau of Forensic Medical Examination, Moscow; Department of Forensic Medicine, Moscow Regional Research and Clinical Institute (MONIKI), Moscow, Russian Federation.<\/span><span class=\"orcid\"><a href=\"https:\/\/orcid.org\/0000-0002-0232-0425\" target=\"_blank\" rel=\"noopener\">\u00a0https:\/\/orcid.org\/0000-0002-0232-0425<\/a><\/span><\/p>\n<p><span class=\"name\"><strong>Olesya V. Veselkina<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Forensic Medicine, Moscow Regional Research and Clinical Institute (MONIKI), Moscow; Department of Innovative Health Care Management, Academy of Postgraduate Education under FSBU FSCC of FMBA of Russia, Moscow, Russian Federation.<\/span><span class=\"orcid\"><a href=\"https:\/\/orcid.org\/0000-0002-9486-5421\" target=\"_blank\" rel=\"noopener\">\u00a0https:\/\/orcid.org\/0000-0002-9486-5421<\/a><\/span><\/p>\n<p><span class=\"name\"><strong>Vladimir A. Klevno<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Forensic Medicine, Moscow Regional Research and Clinical Institute (MONIKI), Moscow, Russian Federation.<\/span><span class=\"orcid\"><a href=\"https:\/\/orcid.org\/0000-0001-5693-4054\" target=\"_blank\" rel=\"noopener\">\u00a0https:\/\/orcid.org\/0000-0001-5693-4054<\/a><\/span><\/p>\n<p><span class=\"name\"><strong>Vasiliy V. Vlassov<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Health Care Management and Economics, National Research University Higher School of Economics, Moscow, Russian Federation.<\/span><span class=\"orcid\"><a href=\"https:\/\/orcid.org\/0000-0001-5203-549X\" target=\"_blank\" rel=\"noopener\">\u00a0https:\/\/orcid.org\/0000-0001-5203-549X<\/a><\/span><\/p>\n<div class=\"item abstract\">\n<h3 class=\"label\">ABSTRACT<\/h3>\n<p><em>Background<\/em>: Poisoning is a critical public health problem. Toxic substances differ across time, region and age. Little is known about poisoning in Russia, and even less is known about lethal poisoning in children in Russia. We aimed to describe the characteristics of cases of lethal poisoning in children and adolescents.<\/p>\n<p><em>Design and methods:<\/em>\u00a0Our retrospective study was based on autopsy reports from archives of the Moscow Region Bureau of Forensic Medical Examination for the period of 2009 to 2018.<\/p>\n<p><em>Results:<\/em>\u00a0A total of 438 lethal poisoning cases were recorded. The average age of the poisoned children was 11.3 years. Deaths predominantly occurred in boys, mostly due to the higher frequency of poisoning with household and technical chemicals (p&lt;0.01). Accidental deaths were also higher in males (p &lt; 0.01). Therapeutic drug poisoning (p&lt;0.01) and suicide (p &lt; 0.01) were more frequent in females.<\/p>\n<p>The leading cause of lethal poisoning in children was exposure to carbon monoxide, especially in children aged 5 to 9 years (p&lt;0.01) and 1 to 4 years (p&lt;0.01). Carbon monoxide poisoning occurred more often in winter (p&lt;0.01). Regarding the structure of poisoning with household and technical chemicals, the most frequent was poisoning by a mixture of utility gases.<\/p>\n<p><em>Conclusion:<\/em> Our study shows that carbon monoxide poisoning is a serious problem in the region. This may be associated with the ongoing use of individual heating systems. A significant increase in the frequency of fatal poisoning by chemicals, especially by propane-butane gas mixtures while sniffing, has become a disturbing trend.<\/p>\n<\/div>\n<div class=\"item references\">\n<h3 class=\"label\">REFERENCES<\/h3>\n<div class=\"value\">\n<p>GBD 2017 DALYs, HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018;392:1859-922. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(18)32335-3\">https:\/\/doi.org\/10.1016\/S0140-6736(18)32335-3<\/a><\/p>\n<p>Sleet DA. The global challenge of child injury prevention. Int J Environ Res Public Health 2018;15:1921. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.3390\/ijerph15091921\">https:\/\/doi.org\/10.3390\/ijerph15091921<\/a><\/p>\n<p>Gummin DD, Mowry JB, Spyker DA, et al. 2017 Annual Report of the American Association of Poison Control Centers&#8217; National Poison Data System (NPDS): 35th Annual Report. Clin Toxicol (Phila) 2018;56:1213-415. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1080\/15563650.2018.1533727\">https:\/\/doi.org\/10.1080\/15563650.2018.1533727<\/a><\/p>\n<p>39th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) 21-24 May 2019, Naples, Italy. Clin Toxicol 2019;57:423-602.<\/p>\n<p>Karadeniz H, Birincioglu I, Turna O, et al. 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Carbon monoxide poisoning in children: Diagnosis and management in the emergency department. Pediatr Emerg Med Pract 2016;13:1-24.<\/p>\n<p>Korppoo A, Korobova N. Modernizing residential heating in Russia: End-use practices, legal developments, and future prospects. Energy Policy 2012;42:213-20. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.enpol.2011.11.078\">https:\/\/doi.org\/10.1016\/j.enpol.2011.11.078<\/a><\/p>\n<p>Filippov SP. Development of centralized district heating in Russia. Thermal Engineering 2009;56:985. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1134\/S0040601509120015\">https:\/\/doi.org\/10.1134\/S0040601509120015<\/a><\/p>\n<p>Winstanley EL, Stover AN. The Impact of the opioid epidemic on children and adolescents. Clin Ther 2019;41:1655-62. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.clinthera.2019.06.003\">https:\/\/doi.org\/10.1016\/j.clinthera.2019.06.003<\/a><\/p>\n<p>Berta GN, Di Scipio F, Bosetti FM, et al. Childhood acute poisoning in the Italian North-West area: a six-year retrospective study. Ital J Pediatr 2020;46:83. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1186\/s13052-020-00845-0\">https:\/\/doi.org\/10.1186\/s13052-020-00845-0<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>https:\/\/doi.org\/10.4081\/jphr.2021.1932 Semyon S. Plis Department of Complex Examinations, Moscow Region Bureau of Forensic Medical Examination, Moscow; Department of Forensic Medicine, Moscow Regional Research and Clinical Institute (MONIKI), Moscow, Russian Federation.\u00a0https:\/\/orcid.org\/0000-0002-0232-0425 Olesya V. Veselkina Department of Forensic Medicine, Moscow Regional Research and Clinical Institute (MONIKI), Moscow; Department of Innovative Health Care Management, Academy of Postgraduate Education &#8230; <a title=\"Acute lethal poisonings in children: a 10-year retrospective study of the Moscow Region, Russia\" class=\"read-more\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1932\/\" aria-label=\"More on Acute lethal poisonings in children: a 10-year retrospective study of the Moscow Region, Russia\">Read more<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-4248","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Acute lethal poisonings in children: a 10-year retrospective study of the Moscow Region, Russia - Journal of Public Health Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1932\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Acute lethal poisonings in children: a 10-year retrospective study of the Moscow Region, Russia - Journal of Public Health Research\" \/>\n<meta property=\"og:description\" content=\"https:\/\/doi.org\/10.4081\/jphr.2021.1932 Semyon S. 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Plis Department of Complex Examinations, Moscow Region Bureau of Forensic Medical Examination, Moscow; Department of Forensic Medicine, Moscow Regional Research and Clinical Institute (MONIKI), Moscow, Russian Federation.\u00a0https:\/\/orcid.org\/0000-0002-0232-0425 Olesya V. Veselkina Department of Forensic Medicine, Moscow Regional Research and Clinical Institute (MONIKI), Moscow; Department of Innovative Health Care Management, Academy of Postgraduate Education ... 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