{"id":4206,"date":"2023-03-27T20:17:47","date_gmt":"2023-03-27T18:17:47","guid":{"rendered":"https:\/\/www.jphres.org\/?p=4206"},"modified":"2023-04-10T08:49:13","modified_gmt":"2023-04-10T06:49:13","slug":"chemical-risk-in-hospital-settings-overview-on-monitoring-strategies-and-international-regulatory-aspects","status":"publish","type":"page","link":"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1993\/","title":{"rendered":"Chemical risk in hospital settings: Overview on monitoring strategies and international regulatory aspects"},"content":{"rendered":"<div class=\"item doi\"><span class=\"value\"><a href=\"https:\/\/doi.org\/10.4081\/jphr.2021.1993\">https:\/\/doi.org\/10.4081\/jphr.2021.1993<\/a><\/span><\/div>\n<ul class=\"item authors\">\n<li><span class=\"name\"><strong>Bruno Charlier<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Albino Coglianese<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy.<\/span><span class=\"orcid\"><br \/>\n<a href=\"https:\/\/orcid.org\/0000-0002-2724-8212\" target=\"_blank\" rel=\"noopener\">https:\/\/orcid.org\/0000-0002-2724-8212<\/a><\/span><\/li>\n<li><span class=\"name\"><strong>Federica De Rosa<\/strong><br \/>\n<\/span><span class=\"affiliation\">University Hospital \u201cSan Giovanni di Dio e Ruggi D\u2019Aragona\u201d, Salerno, Italy.<br \/>\n<\/span><span class=\"orcid\"><a href=\"https:\/\/orcid.org\/0000-0002-5057-4032\" target=\"_blank\" rel=\"noopener\">https:\/\/orcid.org\/0000-0002-5057-4032<\/a><\/span><\/li>\n<li><span class=\"name\"><strong>Francesco De Caro<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Ornella Piazza<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Oriana Motta<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry &#8220;Scuola Medica Salernitana&#8221;, University of Salerno, Baronissi , Italy.<\/span><span class=\"orcid\"><br \/>\n<a href=\"https:\/\/orcid.org\/0000-0003-1088-6741\" target=\"_blank\" rel=\"noopener\">https:\/\/orcid.org\/0000-0003-1088-6741<\/a><\/span><\/li>\n<li><span class=\"name\"><strong>Anna Borrelli<\/strong><br \/>\n<\/span><span class=\"affiliation\">University Hospital \u201cSan Giovanni di Dio e Ruggi d\u2019Aragona\u201d, Salerno, Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Mario Capunzo<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Amelia Filippelli<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy.<\/span><\/li>\n<li><span class=\"name\"><strong>Viviana Izzo<\/strong><br \/>\n<\/span><span class=\"affiliation\">Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy.<\/span><span class=\"orcid\"><br \/>\n<a href=\"https:\/\/orcid.org\/0000-0001-6066-7569\" target=\"_blank\" rel=\"noopener\">https:\/\/orcid.org\/0000-0001-6066-7569<\/a><\/span><\/li>\n<\/ul>\n<div class=\"item abstract\">\n<h3 class=\"label\">ABSTRACT<\/h3>\n<p>Chemical risk in hospital settings is a growing concern that health professionals and supervisory authorities must deal with daily. Exposure to chemical risk is quite different depending on the hospital department involved and might origin from multiple sources, such as the use of sterilizing agents, disinfectants, detergents, solvents, heavy metals, dangerous drugs, and anesthetic gases. Improving prevention procedures and constantly monitoring the presence and level of potentially toxic substances, both in workers (biological monitoring) and in working environments (environmental monitoring), might significantly reduce the risk of exposure and contaminations. The purpose of this article is to present an overview on this subject, which includes the current international regulations, the chemical pollutants to which medical and paramedical personnel are mainly exposed, and the strategies developed to improve safety conditions for all healthcare workers.<\/p>\n<\/div>\n<div class=\"item references\">\n<h3 class=\"label\">REFERENCES<\/h3>\n<div class=\"value\">\n<p>McDiarmid MA. 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High-performance liquid chromatography method for urinary trans, trans-Muconic acid. Application to environmental exposure to benzene. J Anal Toxicol 2006;30:258-61. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1093\/jat\/30.4.258\">https:\/\/doi.org\/10.1093\/jat\/30.4.258<\/a><\/p>\n<p>Inoue O, Seiji K, Suzuki T, et al. Simultaneous determination of hippuric acid, o-, m-, and p-methylhippuric acid, phenylglyoxylic acid, and mandelic acid by HPLC. Bull Environ Contam Toxicol 1991;47:204-10. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1007\/BF01688641\">https:\/\/doi.org\/10.1007\/BF01688641<\/a><\/p>\n<p>Ashfaq M, Noor N, Saif Ur Rehman M, et al. Determination of commonly used pharmaceuticals in hospital waste of Pakistan and evaluation of their ecological risk assessment. Clean Soil Air Water 2017;45:1500392. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1002\/clen.201500392\">https:\/\/doi.org\/10.1002\/clen.201500392<\/a><\/p>\n<p>Viegas S, P\u00e1dua M, Veiga AC, et al.. Antineoplastic drugs contamination of workplace surfaces in two Portuguese hospitals. Environ Monit Assess 2014;186:7807-18. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1007\/s10661-014-3969-1\">https:\/\/doi.org\/10.1007\/s10661-014-3969-1<\/a><\/p>\n<p>G\u00f3mez MJ, Petrovi\u0107 M, Fern\u00e1ndez-Alba AR, Barcel\u00f3 D. Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters. J Chromatogr A 2006;1114:224-33. DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.chroma.2006.02.038\">https:\/\/doi.org\/10.1016\/j.chroma.2006.02.038<\/a><\/p>\n<p>Izzo V, Charlier B, Bloise E, et al. A UHPLC-MS\/MS-based method for the simultaneous monitoring of eight antiblastic drugs in plasma and urine of exposed healthcare workers. J Pharm Biomed Anal 2018;154:245-51. 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DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/S1570-0232(03)00100-4\">https:\/\/doi.org\/10.1016\/S1570-0232(03)00100-4<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"entry_details\">\n<div class=\"item cover_image\">\n<div class=\"sub_item\"><\/div>\n<\/div>\n<div class=\"item galleys\">\n<ul class=\"value galleys_links\">\n<li><a class=\"obj_galley_link pdf\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1993\/\">\u00a0PDF<\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"item published\">\n<div class=\"label\">PUBLISHED<\/div>\n<div class=\"value\">2021-03-24<\/div>\n<\/div>\n<div class=\"item issue\">\n<div class=\"label\">INFO<\/div>\n<section class=\"sub_item\">\n<div class=\"label\"><i class=\"fab fa-leanpub\"><\/i>\u00a0ISSUE<\/div>\n<div class=\"value\"><a class=\"title\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/issue\/view\/32\">Vol 10 No 1 (2021)<\/a><\/div>\n<\/section>\n<section class=\"sub_item\">\n<div class=\"label\"><i class=\"fas fa-tag\"><\/i>\u00a0SECTION<\/div>\n<div class=\"value\">Review Articles<\/div>\n<\/section>\n<\/div>\n<div class=\"item keywords\">\n<div class=\"label\">KEYWORDS:<\/div>\n<div class=\"value\">Occupational medicine, risk assessment, environmental monitoring, biological monitoring, sampling methods<\/div>\n<\/div>\n<div class=\"item published\">\n<div class=\"label\">STATISTICS<\/div>\n<div class=\"value\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li>Abstract views:<span class=\"numero\">45<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li>PDF:<span class=\"numero\">23<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"item citation\">\n<div class=\"sub_item citation_display\">\n<div class=\"label\">HOW TO CITE<\/div>\n<div class=\"value\">\n<div id=\"citationOutput\" role=\"region\" aria-live=\"polite\">\n<div class=\"csl-bib-body\">\n<div class=\"csl-entry\">Charlier, B., Coglianese, A., De Rosa, F., De Caro , F., Piazza, O., Motta, O., Borrelli, A., Capunzo, M., Filippelli, A., &amp; Izzo, V. (2021). Chemical risk in hospital settings: Overview on monitoring strategies and international regulatory aspects.\u00a0<i>Journal of Public Health Research<\/i>,\u00a0<i>10<\/i>(1). https:\/\/doi.org\/10.4081\/jphr.2021.1993<\/div>\n<\/div>\n<\/div>\n<div class=\"citation_formats\"><button class=\"cmp_button citation_formats_button\" aria-controls=\"cslCitationFormats\" aria-expanded=\"false\" data-csl-dropdown=\"true\">More Citation Formats<\/button><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"item copyright\">\n<p>Copyright (c) 2021 The Author(s)<\/p>\n<p>This work is licensed under a\u00a0<a href=\"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\" rel=\"license\">Creative Commons Attribution-NonCommercial 4.0 International License<\/a>.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div id=\"articlesBySameAuthorList\">\n<h3>Most read articles by the same author(s)<\/h3>\n<ul>\n<li>Oriana Motta, Bruno Charlier, Francesco De Caro, Albino Coglianese, Federica De Rosa, Giuseppina Moccia, Concetta Pironti, Mario Capunzo, Anna Borrelli, Amelia Filippelli, Viviana Izzo,\u00a0<a href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/2012\">Environmental and biological monitoring of formaldehyde inside a hospital setting: a combined approach to manage chemical risk in workplaces\u00a0<\/a>,\u00a0<a href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/issue\/view\/32\">Journal of Public Health Research: Vol 10 No 1 (2021)<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div style=\"position: static !important;\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>https:\/\/doi.org\/10.4081\/jphr.2021.1993 Bruno Charlier Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy. Albino Coglianese Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy. https:\/\/orcid.org\/0000-0002-2724-8212 Federica De Rosa University Hospital \u201cSan Giovanni di Dio e Ruggi D\u2019Aragona\u201d, Salerno, Italy. https:\/\/orcid.org\/0000-0002-5057-4032 Francesco De Caro Department &#8230; <a title=\"Chemical risk in hospital settings: Overview on monitoring strategies and international regulatory aspects\" class=\"read-more\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1993\/\" aria-label=\"More on Chemical risk in hospital settings: Overview on monitoring strategies and international regulatory aspects\">Read more<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-4206","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Chemical risk in hospital settings: Overview on monitoring strategies and international regulatory aspects - Journal of Public Health Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.jphres.us.com\/index.php\/jphres\/article\/view\/1993\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemical risk in hospital settings: Overview on monitoring strategies and international regulatory aspects - Journal of Public Health Research\" \/>\n<meta property=\"og:description\" content=\"https:\/\/doi.org\/10.4081\/jphr.2021.1993 Bruno Charlier Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy. Albino Coglianese Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy. https:\/\/orcid.org\/0000-0002-2724-8212 Federica De Rosa University Hospital \u201cSan Giovanni di Dio e Ruggi D\u2019Aragona\u201d, Salerno, Italy. https:\/\/orcid.org\/0000-0002-5057-4032 Francesco De Caro Department ... 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Albino Coglianese Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d, University of Salerno, Baronissi (SA), Italy. https:\/\/orcid.org\/0000-0002-2724-8212 Federica De Rosa University Hospital \u201cSan Giovanni di Dio e Ruggi D\u2019Aragona\u201d, Salerno, Italy. https:\/\/orcid.org\/0000-0002-5057-4032 Francesco De Caro Department ... 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